Protective effects of melatonin against oxidative damage of macromolecules caused by selected potential carcinogens
Published on Friday, 16 October 2015
Abstract
Reactive oxygen species (ROS) and free radicals are essential for physiological processes in living organisms.
However, an overproduction of ROS and free radicals results in enhanced oxidative stress and can lead to several diseases, cancer included.
Certain carcinogens may produce ROS, which directly damage macromolecules, leading to cancer initiation.
It is expected that melatonin, as a well documented antioxidant, may protect macromolecules against oxidative damage caused by certain carcinogens possessing prooxidative properties.
Experimental evidence for the subject in question has been discussed in the survey.
See also About Melatonin.