Vitamin D and cancer

Published on Friday, 21 March 2014

Dihydrotachysterol (DHT) is a synthetic vitamin D analog activated in the liver that does not require renal hydroxylation like vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol) - Di Bella Method

Vitamin D3 or Dihydrotachysterol (synthetic Vitamin D3 - Vitamin D analogues and/or derivatives)


It is a fat-soluble vitamin of which have been identified 7 major varieties among which the most commonly used in therapy are Vitamin D2 or Ergocalciferol and Vitamin D3 or Cholecalciferol.

In tumors, the highest activity is performed by Dihydrotachysterol also called AT10® (or Atiten), preparation antitetanus n. 10, definition due to the tetany state of muscle contraction by calcium deficiency that Dihydrotachysterol antagonizes by increasing calcium levels (others trade/brand name are DHT, DHT Intensol, Hytakerol).

It is synergistic with Retinoids and Melatonin in exercising an antiproliferative, antimetastatic and pro-apoptotic effect in tumors.

An extensive literature has established, emphasized and confirmed the strong activity both preventive and therapeutic action of Vitamin D in neoplastic diseases: In Vitro, In Vivo (Animal Only), Review, Commentary/Editorial/Letter to the Editor/Communication, Meta-analysis/Pooled Analysis/Narrative Reviews and In Vivo (Human Only) publications.


Cell receptors (VDR) on which Vitamin D acts to exert its antineoplastic effects have been recently identified. A new generation of synthetic Vitamin D in which they tried to mitigate the calcemic activity (which is an obstacle because the excess calcium may produce grave damage and not reversible) and increase the antineoplastic one which is synergistic to Retinoids also in the activation of cell differentiation is the subject of numerous studies.

The antiproliferative effect of Vitamin D through the block of cell mitosis in G1 has been explained. It is also relevant the activation of natural immunity and the blocking of angiogenesis in synergy with the other vitamins of Di Bella's method.

In addition to studies on tumor cell lines in vitro and on animals, even epidemiological and clinical studies have confirmed the anti-tumor properties of the Vitamin D and derivatives in the prevention and therapy of tumors. Recently, studies on animals, mainly rats and dogs, have shown a strong antimetastatic activity of Vitamin D.

Di Bella Method and Vitamin D3: 8-10 drops to add to spoon of vitamin (Retinoid) solution, 3 times a day (morning, noon and evening). The dosage can be tripled (consistent with the calcium level, the development of neoplastic disease).


Vitamin D deficiency


Once foods in the United States were fortified with Vitamin D, rickets appeared to have been conquered, and many considered major health problems from Vitamin D deficiency resolved. But Vitamin D deficiency is common. This review considers the role of Vitamin D in skeletal and nonskeletal health (e.g. cancer) and suggests strategies for the prevention and treatment of Vitamin D deficiency.



About this publication.


In a new study, researchers at the UCSD School of Medicine and Moores Cancer Center used a complex computer prediction model to determine that intake of Vitamin D3 and Calcium would prevent 58,000 new cases of breast cancer and 49,000 new cases of colorectal cancer annually in the US and Canada. The researchers model also predicted that 75% of deaths from these cancers could be prevented with adequate intake of Vitamin D3 and Calcium. Join Carole Baggerly with GrassrootsHealth as she discusses this new research.



 Only In Vitro Research (Isolated organs, tissues, cells, or biochemical systems - IUPAC Gold Book definition)


 In Vivo (Animal Only)




 Commentary - Editorial - Letter to the Editor - Communication


 Meta-analysis, Pooled Analysis and Narrative Reviews


 In Vivo (Human Only: Case Reports/Series, Clinical Trials, Comparative Studies, Randomized Controlled Trials and Retrospective Studies)

Vitamin D Status and Survival in Stage II-III Colorectal Cancer